The purpose of this study was to determine the antimicrobial activity of on
e prescription and two commercially available over-the-counter mouthrinses
and positive and negative controls against bacteria commonly found in the o
ral cavity. The bacteria used in this study were Streptococcus mutans, , st
reptococcus sanguis and Actinomyces viscosus. Sterile discs which were trea
ted with the mouthrinses were placed on agar plates along with the controls
. Zones of microbial inhibition were measured in millimeters after 48 hours
. The results indicated that all of the mouthrinses demonstrated antimicrob
ial activity against the bacteria tested. Herbal Mouth and Gum Therapy(R) m
outhrinse, containing natural ingredients, produced the largest zones of mi
crobial inhibition when compared to Listerine(R) against all three of the b
acteria tested. Herbal Mouth and Gum Therapy mouthrinse produced larger zon
es of microbial inhibition when compared to Peridex(R) against two of the t
hree bacteria tested, and produced similar zones of inhibition against the
third bacteria.