Chromosomal mapping of two RBP-J-related genes: Kyo-T and RBP-L

Authors
Tani, S Taniwaki, M Taniguchi, Y Minoguchi, S Kuroda, K Han, H Aoki, T Miyatake, S Hashimoto, N Honjo, T
Citation
S. Tani et al., Chromosomal mapping of two RBP-J-related genes: Kyo-T and RBP-L, J HUM GENET, 44(1), 1999, pp. 73-75
Citations number
13
Categorie Soggetti
Molecular Biology & Genetics
Journal title
JOURNAL OF HUMAN GENETICS
ISSN journal
14345161 → ACNP
Volume
44
Issue
1
Year of publication
1999
Pages
73 - 75
Database
ISI
SICI code
1434-5161(1999)44:1<73:CMOTRG>2.0.ZU;2-4
Abstract
We have recently isolated two genes encoding proteins which have either hom ology or affinity to RBP-J, a transcription factor involved in Notch signal ing. Kyo-T interacts with RBP-J and possibly regulates the function of RBP- J. RBP-L has a highly homologous region with REP J but the function of RBP- L is unknown. Fluorescence in situ hybridization analysis of human metaphas e chromosomes localized Kyo-T and RBP-L to Xq26 and 20q12-13.1, respectivel y.