dWe describe a 4 month old male with a de novo interstitial deletion of chr
omosome 10q22. His clinical features included growth deficiency, developmen
tal delay, ocular hypertelorism, posteriorly rotated ears, retrognathia, an
d fifth finger clinodactyly. He later developed dental lamina cysts of the
alveolar ridge. To our knowledge, this is the first reported case of an int
erstitial deletion of 10q22.