M. Mussat et al., A constructionist model predicting the emergence, complementarity and classification of the nucleotide bases, MED HYPOTH, 51(6), 1998, pp. 511-523
Citations number
24
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
We are proposing an analytical matrix that models a logical process simulat
ing the emergence of the bases of vital nucleotides. The construction and p
roperties of the matricial model are outlined. The Graph 1 matrix specifies
a unique distribution pattern of eight terms coded in binary triplet confi
gurations and obeys specific dynamic laws. The whole set of binary triplet
configurations is in dynamic equilibrium. For that reason, it is possible t
o carry out an analysis by entering by any one of the eight terms on the co
ndition that the operating mode obeys all the internal laws of orientation
and symmetries inherent in the matrix. The four chemical elements at the or
igin of life are distributed following their atomic structures in the order
hydrogen (H), carbon (C), nitrogen (N) and oxygen (O) and organized accord
ing to the model. The dynamic properties of the model necessitate the runni
ng of three successive circular periodic studies per analysis in order to s
how the emergence of the four bases - adenine, guanine, cytosine and thymin
e - precisely in that order. The fifth base of the nucleotides - uracil - s
hows up twice but always in an intermediate position, thus in transition, a
s it is the case for messenger ribonucleic acid (mRNA). We show also that t
he model provides for a logical explanation of the law of complementarity o
f the bases and their chemical classification. It is proposed that subseque
nt developments of the dynamic laws of this matrix may lead to the study of
the logical operations for the formation of protein sequences and of their
analysis and to genetic bioprogramming in general. Thus, a strictly logica
l and dynamic approach to molecular genetics is possible.