Most algorithms developed by various investigators for use in brachytherapy
treatment planning have typically been designed to calculate the dose with
in a 10 cm range of a radiation source. These algorithms predict the dose w
ell at distances <10 cm from the source but were not developed and should n
ot be utilized to predict the dose at distances >10 cm. On the contrary, tr
eatment planning systems and manual calculations will produce erroneous res
ults when dose points >10 cm are calculated using these algorithms. The spr
ead in the data generated by the above algorithms is 16% at 15 cm and 42% a
t 20 cm. Physical measurements were performed at distances between 5 and 50
cm from a high activity Ir-192 source in water. The measured data correlat
ed well with the predicted data from 5 to 10 cm, which had a 5% spread. Bey
ond 10 cm the measured data fell central to the range of the predicted data
, with the spread of the predicted data increasing from 5% to 80% with incr
easing distance from the source. The measured data was fitted with a model
incorporating a buildup factor and an attenuation factor. The best fit valu
es are in reasonable agreement with those obtained by two of the investigat
ors, Thomason and Tripathi. (C) 1999 American Association of Physicists in
Medicine. [S0094-2405(99)01001-9].