Purpose: To describe new software developments in videokeratography an
d illustrate their application in patients with corneal disease or pat
ients who have had keratorefractive surgery. Methods: The Holladay Dia
gnostic Summary provides 4 maps and 15 corneal parameters for the clin
ician. The maps include 2 refractive power maps on standard and auto s
cales, a profile difference map for determining the corneal shape rela
tive to normal asphericity, and a distortion map to display the optica
l quality of the cornea. The 15 corneal parameters provide quantitativ
e information about the cornea for a 3.0 mm pupil; e.g., effective ref
ractive power, regular astigmatism, asphericity, and predicted corneal
acuity. The maps and parameters are used to analyze a calibration bal
l and five clinical examples. Results: Patients with diseases such as
keratoconus or patients who have had keratorefractive surgery have cha
racteristic changes in the 4 maps and the 15 corneal parameters. Concl
usion: When true refractive power maps, a profile difference map, a di
stortion map, and 15 corneal parameters are analyzed, characteristic c
hanges are found that can help clinicians recognize and monitor cornea
l disease and refractive surgery and correlate these changes with pati
ents' visual symptoms.