Purpose: To investigate a possible relationship between evisceration and sy
mpathetic ophthalmia.
Methods: Data from Mt. Sinai Medical Center and University Hospital of Clev
eland were collected and histopathologic specimens were reviewed for 51 of
90 patients who underwent evisceration between 1980 and 1996 and who return
ed for follow-up examinations. Additionally, a survey was sent to members o
f the American Society of Ophthalmic Plastic and Reconstructive Surgery, th
e Uveitis Society, and the Eastern Ophthalmic Pathology Society to determin
e the number of enucleations and eviscerations performed and the documented
incidence of sympathetic ophthalmia after evisceration.
Results: No clinical or histopathologic evidence of sympathetic ophthalmia
after evisceration was found among patients treated at the two medical cent
ers. The collective surveys showed a strong preference for enucleation over
evisceration, but did not document evidence of sympathetic ophthalmia afte
r evisceration.
Conclusions: Evisceration is an effective and safe procedure with a low ris
k for sympathetic ophthalmia.