Antiaggregant effects on human platelets of culinary herbs

Authors
Okazaki, K Nakayama, S Kawazoe, K Takaishi, Y
Citation
K. Okazaki et al., Antiaggregant effects on human platelets of culinary herbs, PHYTOTHER R, 12(8), 1998, pp. 603-605
Citations number
4
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHYTOTHERAPY RESEARCH
ISSN journal
0951418X → ACNP
Volume
12
Issue
8
Year of publication
1998
Pages
603 - 605
Database
ISI
SICI code
0951-418X(199812)12:8<603:AEOHPO>2.0.ZU;2-G
Abstract
The inhibitory effects of methanol extracts of 20 herb species on human pla telet aggregation were investigated. Allspice, basil, marjoram, tarragon an d thyme strongly inhibited the platelet aggregation induced by collagen. Ba sil, marjoram and tarragon strongly inhibited platelet aggregation induced by ADP. An active compound, arbutin, was isolated from sweet marjoram as an inhibitor of platelet aggregation induced by collagen; ADP, arachidonic ac id (AA) and thrombin. (C) 1998 John Wiley & Sons, Ltd.