A practical method for the preparation of nitriles from primary amides under non-acidic conditions

Authors
Bose, DS Jayalakshmi, B
Citation
Ds. Bose et B. Jayalakshmi, A practical method for the preparation of nitriles from primary amides under non-acidic conditions, SYNTHESIS-S, (1), 1999, pp. 64-65
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
1
Year of publication
1999
Pages
64 - 65
Database
ISI
SICI code
0039-7881(199901):1<64:APMFTP>2.0.ZU;2-6
Abstract
In order to establish a mild conversion method of primary amides to nitrile s, various types of carboxamides were treated with trifluoromethanesulfonic anhydride and triethylamine, as a dehydrating agent to obtain the desired nitriles in 84-95% yields.