Lewis acid-mediated selective removal of N-tert-butoxycarbonyl protective group (t-Boc)

Authors
Bose, DS Lakshminarayana, V
Citation
Ds. Bose et V. Lakshminarayana, Lewis acid-mediated selective removal of N-tert-butoxycarbonyl protective group (t-Boc), SYNTHESIS-S, (1), 1999, pp. 66-68
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
1
Year of publication
1999
Pages
66 - 68
Database
ISI
SICI code
0039-7881(199901):1<66:LASRON>2.0.ZU;2-7
Abstract
A simple and efficient method for the selective cleavage of N-Boc protectiv e groups from amines employing Lewis acid aluminum chloride, is described. The scope of this procedure is explored for the deprotection of a variety o f amines including amino acid derivatives.