An efficient synthesis of 4-aryl kainic acid analogs

Citation
H. Maeda et al., An efficient synthesis of 4-aryl kainic acid analogs, TETRAHEDRON, 55(4), 1999, pp. 943-954
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
4
Year of publication
1999
Pages
943 - 954
Database
ISI
SICI code
0040-4020(19990122)55:4<943:AESO4K>2.0.ZU;2-0
Abstract
A synthesis of 4-aryl kainic acid analogs was achieved using a highly stere oselective Michael addition reaction of dimethyl 2-oxoglutarate with a nitr ostyrene. Nitro group reduction, deoxygenation and epimerization complete t he synthetic route. (C) 1999 Elsevier Science Ltd. All rights reserved.