Novel 2 '-deoxycytidine analogues as pH independent substitutes of protonated cytosines in triple helix forming oligonucleotides

Authors
Bedu, E Benhida, R Devys, M Fourrey, JL
Citation
E. Bedu et al., Novel 2 '-deoxycytidine analogues as pH independent substitutes of protonated cytosines in triple helix forming oligonucleotides, TETRAHEDR L, 40(5), 1999, pp. 835-838
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
5
Year of publication
1999
Pages
835 - 838
Database
ISI
SICI code
0040-4039(19990129)40:5<835:N2'AAP>2.0.ZU;2-B
Abstract
The N-acetyl derivatives 1a and 2a of the aminotriazole and aminoimidazole 2'-deoxynucleosides 1 and 2 were synthesized as potential substitutes of pr otonated 2'-deoxycytidines within triple helix forming oligonucleotides for their recognition of DNA duplexes in a pH independent manner. (C) 1999 Els evier Science Ltd. All rights reserved.