Catalytic antibodies: Possible applications in organic synthesis

Authors
Citation
Nk. Kochetkov, Catalytic antibodies: Possible applications in organic synthesis, USP KH, 67(12), 1998, pp. 1099-1132
Citations number
123
Categorie Soggetti
Chemistry
Journal title
USPEKHI KHIMII
ISSN journal
00421308 → ACNP
Volume
67
Issue
12
Year of publication
1998
Pages
1099 - 1132
Database
ISI
SICI code
0042-1308(1998)67:12<1099:CAPAIO>2.0.ZU;2-G
Abstract
The data on catalytic antibodies as a new generation of biocatalysts are re viewed. The principles used in the design and the methods for preparation o f all presently known classes of catalytic antibodies are discussed in term s of conversions of various organic compounds catalysed by them. The data o n the efficiency, regio- and stereospecificity and mechanisms of action of catalytic antibodies are presented and their possible applications in fine organic synthesis are considered.