Effect of acute testosterone on myocardial ischemia in men with coronary artery disease

Authors
Webb, CM Adamson, DL de Zeigler, D Collins, P
Citation
Cm. Webb et al., Effect of acute testosterone on myocardial ischemia in men with coronary artery disease, AM J CARD, 83(3), 1999, pp. 437
Citations number
22
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
83
Issue
3
Year of publication
1999
Database
ISI
SICI code
0002-9149(19990201)83:3<437:EOATOM>2.0.ZU;2-L
Abstract
The effect of acute testosterone administration on exercise-induced myocard ial ischemia was assessed in 14 men with coronary artery disease and low pl asma testosterone concentrations in a study of randomized, double-blind, cr ossover design. Testosterone increased time to 1-mm ST-segment depression c ompared with placebo by 66 (15 to 117) seconds (p = 0.016), suggesting a be neficial effect of testosterone on myocardial ischemia in these patients.