Does angiotensin-converting enzyme polymorphism influence the clinical manifestation and progression of pearl failure in patients with dilated cardiomyopathy?

Authors
Vancura, V Hubacek, J Malek, I Gebauerova, M Pit'ha, J Dorazilova, Z Langova, M Zelizko, M Poledne, R
Citation
V. Vancura et al., Does angiotensin-converting enzyme polymorphism influence the clinical manifestation and progression of pearl failure in patients with dilated cardiomyopathy?, AM J CARD, 83(3), 1999, pp. 461
Citations number
9
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
83
Issue
3
Year of publication
1999
Database
ISI
SICI code
0002-9149(19990201)83:3<461:DAEPIT>2.0.ZU;2-H
Abstract
To evaluate the role of angiotensin-converting enzyme (ACE) polymorphism on the development of end-stage dilated cardiomyopathy, the ACE gene polymorp hism of 90 patients after heart transplantation because of this disease was compared with the population sample. No difference in gene frequencies was found, but when compared with the population sample there were fewer ID he terozygotes detected; no significant influence of ACE polymorphism on the c ourse of the disease before transplantation was found.