Relation of fibrinolytic potentiation by estrogen to coagulation pathway activation in postmenopausal women

Authors
Koh, KK Horne, MK Csako, G Waclawiw, MA Cannon, RO
Citation
Kk. Koh et al., Relation of fibrinolytic potentiation by estrogen to coagulation pathway activation in postmenopausal women, AM J CARD, 83(3), 1999, pp. 466
Citations number
18
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
83
Issue
3
Year of publication
1999
Database
ISI
SICI code
0002-9149(19990201)83:3<466:ROFPBE>2.0.ZU;2-7
Abstract
To determine whether enhanced fibrinolysis is a primary effect of estrogen or is secondary to activation of coagulation, we measured hemostatic factor s before and after conjugated equine estrogen 0.625 mg/day for 1 month in 9 postmenopausal women. We found that potentiation of fibrinolysis is a prim ary effect of conjugated equine estrogens at this commonly used dosage in h ealthy postmenopausal women.