Human MRP3 transporter: identification of the 5 '-flanking region, genomicorganization and alternative splice variants

Authors
Fromm, MF Leake, B Roden, DM Wilkinson, GR Kim, RB
Citation
Mf. Fromm et al., Human MRP3 transporter: identification of the 5 '-flanking region, genomicorganization and alternative splice variants, BBA-BIOMEMB, 1415(2), 1999, pp. 369-374
Citations number
18
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
ISSN journal
00052736 → ACNP
Volume
1415
Issue
2
Year of publication
1999
Pages
369 - 374
Database
ISI
SICI code
0005-2736(19990108)1415:2<369:HMTIOT>2.0.ZU;2-E
Abstract
In humans, at least six members of the multidrug resistance-associated prot ein (MRP) family are thought to exist. Here we report the molecular cloning of two splice variants of MRP3 from human liver. In addition, MRP3 genomic organization including the 5'-flanking region and a major portion of the M RP3 intron-exon organization are identified and characterized. (C) 1999 Pub lished by Elsevier Science B.V. All rights reserved.