Cloning and sequencing of a secretory 28-kDa protein from rat olfactory epithelium

Authors
Andreeva, SG Merkulova, MI Shuvaeva, TM Novoselov, VI Peshenko, IV Novoselov, SV Fesenko, EE Lipkin, VM
Citation
Sg. Andreeva et al., Cloning and sequencing of a secretory 28-kDa protein from rat olfactory epithelium, BIOORG KHIM, 24(11), 1998, pp. 816-821
Citations number
17
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANICHESKAYA KHIMIYA
ISSN journal
01323423 → ACNP
Volume
24
Issue
11
Year of publication
1998
Pages
816 - 821
Database
ISI
SICI code
0132-3423(199811)24:11<816:CASOAS>2.0.ZU;2-1
Abstract
Clone lambda a26.1 isolated from rat olfactory epithelium contains a full-l ength 28-kDa protein cDNA (1414 b. p.). The reconstructed protein sequence comprises 223 aa with a calculated molecular mass of 24 630 Da. A substanti al homology was revealed between the amino acid sequence of the 28-kDa prot ein and those of thiol-specific antioxidants (peroxiredoxines). The 28-kDa protein belongs to the 1Cys-subfamily of peroxiredoxines and is the first m ember of peroxiredoxines identified in the olfactory epithelium.