This study investigated the relationships among several aspects of cognitiv
e functioning and the outcome of self-medication training in hospitalized e
lderly patients. Data from 53 geriatric patients who received rehabilitatio
n treatment at the SCO Hospital in Ottawa, Canada between 1992 and 1997 wer
e collected, on an archival basis. Patients began a graduated self-medicati
on program after undergoing a neuropsychological evaluation. Performance sc
ores from five different aspects of cognition were regressed on the self-me
dication training outcome measures. Findings revealed that aspects of cogni
tive functioning were significantly related to the outcome of self-medicati
on training. Thus, psychometric measures of cognition can be useful in pred
icting which patients are most likely to benefit from a self-medication pro
gram, or alternatively, those who would require a modified program to be ab
le to learn. The clinical implications of these results are discussed.