Synthesis and study of an acridine substituted Troger's base: preferentialbinding of the (-)-isomer to B-DNA

Authors
Tatibouet, A Demeunynck, M Andraud, C Collet, A Lhomme, J
Citation
A. Tatibouet et al., Synthesis and study of an acridine substituted Troger's base: preferentialbinding of the (-)-isomer to B-DNA, CHEM COMMUN, (2), 1999, pp. 161-162
Citations number
23
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
2
Year of publication
1999
Pages
161 - 162
Database
ISI
SICI code
1359-7345(19990121):2<161:SASOAA>2.0.ZU;2-N
Abstract
The acridine substituted Troger's base 4 was prepared, resolved and the (-) -(7R,17R) enantiomer was shown to bind preferentially to calf-thymus B-DNA.