Bis(2-methoxyethyl)aminosulfur trifluoride: a new broad-spectrum deoxofluorinating agent with enhanced thermal stability

Authors
Lal, GS Pez, GP Pesaresi, RJ Prozonic, FM
Citation
Gs. Lal et al., Bis(2-methoxyethyl)aminosulfur trifluoride: a new broad-spectrum deoxofluorinating agent with enhanced thermal stability, CHEM COMMUN, (2), 1999, pp. 215-216
Citations number
11
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
2
Year of publication
1999
Pages
215 - 216
Database
ISI
SICI code
1359-7345(19990121):2<215:BTANBD>2.0.ZU;2-4
Abstract
Bis(2-methoxyethyl)aminosulfur trifluoride (Deoxo-Fluor(TM)) is effective f or the conversion of alcohols to alkyl fluorides, aldehydes/ketones to the corresponding gem-difluorides and also for the transformation of carboxylic acids to their trifluoromethyl derivatives; it is a less thermally sensiti ve, broader-spectrum alternative to the traditional dialkylaminosulfur trif luoride (DAST) deoxofluorination reagents.