Fine-needle aspiration biopsy using a newly-developed pencil-grip syringe holder

Until now commercially available syringe holders for fine-needle aspiration (FNA) were designed to be held in a pistol-grip manner A newly developed, pencil-grip syringe holder the Tao Aspirator(TM), was tested. The device is equipped with a release button for automatically drawing back the syringe plunger and a regulating knob for adjusting negative pressure for the aspir ation. After direct smears were made for on-site examination, the remaining aspirated material was collected by rinsing the needle and syringe with Cy toRich red fixative. Hettich cytocentrifuge preparations were then prepared . The quality of the first 150 FNA specimens procured by this device and pr epared with liquid fixation was evaluated in terms of adequacy of specimen, amount of obscuring blood preservation of cells, and ease of screening and interpretation. These 150 specimens included 32 from thyroids; 34 from bre asts; 40 from lymph nodes; 24 from subcutaneous nodules; and 20 from saliva ry glands. There were no unsatisfactory specimens. In Hettich preparations, red blood cells were lysed making interpretation easier All cellular eleme nts and tissue fragments were adequately fixed, showing excellent cellular morphology. Specimens fixed in liquid fixative yielded uniform cell suspens ions, resulting in cytocentrifuge preparations with evenly distributed cell s, and so the screening was also easier: The aspiration techniques using pi stol-grip and pencil-grip FNA syringe holders were also compared in terms o f control in tissue sampling, ease of use, and safety The pencil-grip syrin ge holder allowed greater tactile sensation of the texture of the lesion, a nd enabled the operator to use a single hand to place a needle into a targe t lesion with minimal error This device placed the hand relatively close to the needle rip while the hand was in a position of natural function, impar ting more control in tissue sampling, It was more easily manipulated and co uld prevent dripping when cystic fluid was aspirated. Specimen collection u sing the Tao Aspirator(TM) and processing with liquid fixation in addition to direct smear preparations allowed the laboratory to consistently produce adequate cytologic preparations and cell blocks. (C) 1999 Wiley-Liss, Inc.