Anaplastic nodules in an ovarian mucinous tumor. Case report and literature review

The case of a 38-year-old woman with an ovarian mucinous cyst that containe d solid nodules of anaplastic carcinoma is described. Hitherto, only 17 cas es of this aggressive type of ovarian tumor have been reported. The patient underwent a total abdominal hysterectomy with bilateral salpingo-oophorect omy and a para-aortic and pelvic lymphadenectomy. The tumor was classified as FIGO Stage Ic. On flow cytometry the tumor was DNA diploid. Also. on ima ge analysis the regions with well- differentiated carcinoma and the regions with anaplastic nodules were DNA diploid. No adjuvant treatment was given. There is no evidence of disease 30 months after diagnosis.