New synthetic routes for antimicrobial mesoionics 4-methyl-1.3.4-thiadiazol
ium-2-aminide and 4-aryl-1.3.4-thiadiazolium-2-aminide and their precursors
are reported. Through the reported procedure, antimicrobial 1.4-diaroyl-th
iosemicarbazides can be obtained in high purity degree.