HUMFIBRA allele distribution in northern Poland using capillary electrophoresis

Authors
Citation
R. Pawlowski, HUMFIBRA allele distribution in northern Poland using capillary electrophoresis, INT J LEGAL, 112(2), 1999, pp. 139-141
Citations number
10
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
ISSN journal
09379827 → ACNP
Volume
112
Issue
2
Year of publication
1999
Pages
139 - 141
Database
ISI
SICI code
0937-9827(199901)112:2<139:HADINP>2.0.ZU;2-V
Abstract
Amplification products of the HUMFIBRA locus were analysed in a population from Northern Poland using capillary electrophoresis. The most frequent all eles were 21, 22 and 20 with a frequencies of 0.201, 0.179 and 0.167 respec tively, and five rare variants were observed with frequencies less than 0.0 15. A homogeneous allele distribution was found between Polish and Dutch po pulations and significant differences between Poles and Italians. The high discrimination power (0.963), polymorphic information content (0.849) and h eterozygosity confirm the usefulness of HUMFIBRA locus for forensic identif ication purposes. The application of capillary electrophoresis offers the p ossibility of precise identification of rare variants.