Growth and digestion studies were conducted to evaluate the use of ard
acin as a feed-grade antibiotic for enhancing digestive function and g
rowth in grazing steers. In Exp. 1, 90 yearling steers (average initia
l BW of 248 kg) used in a randomized complete block design (block = we
ight group) grazed fescue pasture without supplementation (CON) or wit
h daily supplements (DM basis) of .4% of BW supplemental ground corn (
CRN) or .4% of BW supplemental corn supplying 120 mg of ardacin (ARD).
In Exp. 2, 12 ruminally and duodenally cannulated steers and three ru
minally cannulated steers (Hereford x Angus; average BW of 347 kg) wer
e used to evaluate the effects of the same supplements used in Exp. 1
on ruminal fermentation and digestion. In Exp. 1, ARD-supplemented ste
ers weighed more (P < .01) at the conclusion of the study than CRN ste
ers, which together weighed more (P < .01) than CON steers. Average da
ily gain was greater (P < .10) in supplemented than in CON steers; ARD
steers had greater (P < .01) ADG than CRN steers. In Exp. 2, forage i
ntake and harvesting efficiency did not vary (P > .10) with supplement
ation or type of supplement, but total intake reflected (P = .03) the
addition of corn to the forage diet. Addition of ardacin increased (P
= .02) ruminal pH compared with CRN steers. Ardacin decreased ruminal
molar proportions of acetate and increased (P = .01) propionate propor
tions when compared with CRN steers. Total tract N digestibility was a
ffected (P < .10) by supplementation and by addition of ardacin to the
diet. Addition of ardacin to the ground corn supplement increased ADG
, in part by enhancing acetate:propionate ratios and increasing N dige
stion.