The use of arterial allografts in aortic graft infections - A three year experience on eighteen patients

Background. We describe our experience in the treatment of aortic graft inf ections by replacing them with arterial homografts as suggested by the good results recently described. Methods. Between March 1994 and March 1997 eighteen patients with infection s of the aortofemoral bifurcation segments have been treated. All patients underwent a complete explantation of the infected graft and an in situ reva scularization with arterial homograft harvested in multiorgan removal. Eigh t segments were freshly preserved, 10 were cryopreserved. Four patients wer e operated as emergencies, of which 3 for aorto-enteric fistulas. All other s presented a serious septic state. Results. Three patients died in the early postoperative period: one of acut e infarction and two of homograft related causes. in the follow-up there wa s only one death from acute infarction, a branch occlusion and two allograf t enteric fistulas successfully treated by surgery. All surviving patients are submitted to periodical haemodynamic and tomographic control with an av erage follow-up of 22 months (range 3 months to 3 years) and there has been no allograft degeneration so far, Conclusions. The use of homologue arterial allografts has shown good result s in the treatment of serious aortic graft infections resulting in adequate peripheral vascularization. There have been no significant degenerations t o date, either in fresh or cryopreserved allografts.