Osteoinduction by calcium phosphate biomaterials

Different materials were implanted in muscles of dogs to study the osteoind uction of calcium phosphate biomaterials. Bone formation was only seen in c alcium phosphate biomaterials with micropores, and could be found in hydrox yapatite (HA) ceramic, tricalcium phosphate/hydroxyapatite ceramic (BCP), b eta-TCP ceramic and calcium phosphate cement. The osteoinductive potential was different in different materials. The results indicate that osteoinduct ion can be a property of calcium phosphate biomaterials when they exhibit s pecific chemical and structural characteristics. (C) 1998 Kluwer Academic P ublishers.