Angiosarcoma of the tongue: report of a case with immunohistochemical findings

Authors
Tabata, M Sugihara, K Matsui, R Yonezawa, S Abeyama, K Maruyama, I
Citation
M. Tabata et al., Angiosarcoma of the tongue: report of a case with immunohistochemical findings, J ORAL PATH, 28(2), 1999, pp. 92-95
Citations number
24
Categorie Soggetti
da verificare
Journal title
JOURNAL OF ORAL PATHOLOGY & MEDICINE
ISSN journal
09042512 → ACNP
Volume
28
Issue
2
Year of publication
1999
Pages
92 - 95
Database
ISI
SICI code
0904-2512(199902)28:2<92:AOTTRO>2.0.ZU;2-P
Abstract
A case report of angiosarcoma of the tongue is presented. The specimen reve aled single and clustered large, pleomorphic, and spindle-shaped cells with a markedly hemorrhagic background. Tumor cells showed expression of thromb omodulin and E-selectin. but no expression of Factor VIII-related antigen, Ulex europaeus agglutinin-I, vascular endothelial growth factor, and CD34. In the current study, immunohistochemical results using antibodies against thrombomodulin and E-selection supported the diagnosis of angiosarcoma.