Metathesis-based synthesis of jasmonate and homojasmonate lactones, candidates for extracellular quorum sensing molecules in Candida albicans

Authors
Cho, SC Dussault, PH Lisec, AD Jensen, EC Nickerson, KW
Citation
Sc. Cho et al., Metathesis-based synthesis of jasmonate and homojasmonate lactones, candidates for extracellular quorum sensing molecules in Candida albicans, J CHEM S P1, (2), 1999, pp. 193-196
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
2
Year of publication
1999
Pages
193 - 196
Database
ISI
SICI code
0300-922X(19990121):2<193:MSOJAH>2.0.ZU;2-5
Abstract
Ring-closing metathesis of jasmonate esters is shown to provide a rapid ent ry to jasmonate lactones. The lactones were investigated as possible quorum sensing molecules for the fungi Candida albicans. Assays demonstrated no e ffect on fungal morphology at concentrations up to 96 mu M.