Bilateral optic neuropathy with IgG kappa multiple myeloma improved after myeloablative chemotherapy

Authors
Lieberman, FS Odel, J Hirsh, J Heinemann, M Michaeli, J Posner, J
Citation
Fs. Lieberman et al., Bilateral optic neuropathy with IgG kappa multiple myeloma improved after myeloablative chemotherapy, NEUROLOGY, 52(2), 1999, pp. 414-416
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
52
Issue
2
Year of publication
1999
Pages
414 - 416
Database
ISI
SICI code
0028-3878(19990115)52:2<414:BONWIK>2.0.ZU;2-7
Abstract
A 49-year-old woman with immunoglobulin G kappa multiple myeloma developed progressive visual loss with bilateral upper and lower central arcuate scot omas. Funduscopic and electrophysiologic studies indicated bilateral optic neuropathy. The immunoglobulin G fraction of the patient's serum reacted wi th retinal ganglionic cells in bovine retina. The visual abnormalities remi tted after myeloablative chemotherapy and disappearance of the paraprotein.