Intracranial leiomyosarcoma in a patient with AIDS

We report an intracranial leiomyosarcoma in the pontine cistern of a 34-yea r-old woman infected with the human immunodeficiency virus (HIV), The clini cal, radiological and pathological data are reviewed. The tumor was Epstein -Barr virus (EBV) positive by in situ hybridization. This case emphasizes t hat smooth muscle neoplasms arising in the setting of immunocompromise can occur intracranially, and corroborates a hypothesis that EBV coinfection ma y have a role in development of these tumors.