Background "America's Best Hospitals," an influential list published annual
ly by U.S. News & World Report, assesses the quality of hospitals. It is no
t known whether patients admitted to hospitals ranked at the top in cardiol
ogy have lower short-term mortality from acute myocardial infarction than t
hose admitted to other hospitals or whether differences in mortality are ex
plained by differential use of recommended therapies.
Methods Using data from the Cooperative Cardiovascular Project on 149,177 e
lderly Medicare beneficiaries with acute myocardial infarction in 1994 or 1
995, we examined the care and outcomes of patients admitted to three types
of hospitals: those ranked high in cardiology (top-ranked hospitals); hospi
tals not in the top rank that had on-site facilities for cardiac catheteriz
ation, coronary angioplasty, and bypass surgery (similarly equipped hospita
ls); and the remaining hospitals (non-similarly equipped hospitals). We com
pared 30-day mortality; the rates of use of aspirin, beta-blockers, and rep
erfusion; and the relation of differences in rates of therapy to shortterm
mortality.
Results Admission to a top-ranked hospital was associated with lower adjust
ed 30-day mortality (odds ratio, 0.87; 95 percent confidence interval, 0.76
to 1.00; P = 0.05 for top-ranked hospitals vs. the others). Among patients
without contraindications to therapy, top-ranked hospitals had significant
ly higher rates of use of aspirin (96.2 percent, as compared with 88.6 perc
ent for similarly equipped hospitals and 83.4 percent for non-similarly equ
ipped hospitals; P < 0.01) and beta-blockers (75.0 percent vs. 61.8 percent
and 58.7 percent, P < 0.01), but lower rates of reperfusion therapy (61.0
percent vs. 70.7 percent and 65.6 percent, P = 0.03). The survival advantag
e associated with admission to top-ranked hospitals was less strong after w
e adjusted for factors including the use of aspirin and beta-blockers (odds
ratio, 0.94; 95 percent confidence interval, 0.82 to 1.08; P = 0.38).
Conclusions Admission to a hospital ranked high on the list of "America's B
est Hospitals" was associated with lower 30-day mortality among elderly pat
ients with acute myocardial infarction. A substantial portion of the surviv
al advantage may be associated with these hospitals' higher rates of use of
aspirin and beta-blocker therapy. (N Engl J Med 1999;340: 286-92.) (C) 199
9, Massachusetts Medical Society.