Reduced health care budgets are expected to inhibit the progress in medicin
e and to lower the quality of medical care. We postulate that these expecta
tions are not justified if decisions in medicine will be based on scientifi
c criteria. Using a clinical scenario we try to describe the difference bet
ween true medical progress and application of new techniques. We also try t
o give reasons for the advantage of differentiation between effectiveness a
nd benefit of medical care. This differentiation leads to a hierarchy of cl
inical-economic decisions, first on effectiveness and subsequently on effic
iency. Effectiveness of medical care is assessed in the dimensions of effic
acy, effectiveness, and benefit. Efficiency is assessed in the dimensions o
f patient's preference, patient's compliance, and the relation of costs and
consequences. Finally we use three examples to discuss the advantages of t
hese assessments and the possibility of their realization. A necessary cond
ition for this realization is the conceptual change from an effectiveness-o
riented medicine to a benefit-oriented one. If we are ready to support futu
re decisions on health care services by solid scientific evidence, we will
sooner or later realize the huge gap in and the resulting need for relevant
data on health care decisions. This need of investments will bind free res
ources and will, if adequately directed, lead to a new and large area of se
rvices provided by physicians the setup of a comprehensive health care data
base. From these changes in medicine we can expect a reduction in the numb
er of provided services which are characterized either by low effectiveness
or by low efficiency (low eff services). This reduction step will be pract
icable only if its economic component is compensated by other - more effect
ive or more efficient - services. The rewarded setup of a comprehensive hea
lth care data base is one of these meaningful and urgently needed possibili
ties. Following this way it is rather unlikely that progress in medicine wi
ll be inhibited; it is rather likely that the necessary resources for finan
cing the progress in medicine will be not bound by low eff services but wil
l really be available to pay for urgently needed information.