Chemoenzymic synthesis of the G(M3)-oligosaccharide [NeuNAc alpha(2-3)Gal beta(1-4)Glc] on a water-soluble polymer support

Authors
Tuchinsky, A Zehavi, U
Citation
A. Tuchinsky et U. Zehavi, Chemoenzymic synthesis of the G(M3)-oligosaccharide [NeuNAc alpha(2-3)Gal beta(1-4)Glc] on a water-soluble polymer support, REACT FUNCT, 39(2), 1999, pp. 147-153
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
REACTIVE & FUNCTIONAL POLYMERS
ISSN journal
13815148 → ACNP
Volume
39
Issue
2
Year of publication
1999
Pages
147 - 153
Database
ISI
SICI code
1381-5148(19990215)39:2<147:CSOTG[>2.0.ZU;2-T
Abstract
A water-soluble polymer, carrying 0.16 meq of lactose/g was prepared follow ing the copolymerization of 2-nitro-4-(carboxyhydrazido-N-aclyloyl)benzyl 2 ,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-beta -D-glucopyranoside and acrylamide. Subsequently, employing a sialyltransfer ase-phosphatase system a NeuNAc-residue was transferred photochemical relea se, the free G(M3)-oligosaccharide [NeuNAc alpha(2-3)Gal beta(1-4)Glc]. (C) 1999 Elsevier Science B.V. All rights reserved.