Bone metastases from bronchial carcinoid tumors - Two case-reports

Two case-reports of metastatic bone disease in patients with bronchial carc inoid tumors illustrate the diagnostic challenges raised by these slowly-gr owing malignancies of which the primary frequently escapes early identifica tion. The first patient had the typical picture of a primary with a single bone metastasis. Unusual features in the second patient were the large numb er of bone metastases, involvement of distal skeletal sites, and elevation of serotonin and 5-hydroxyindoleacetic acid levels.