Epidermal enzymes: Their role in homeostasis and their relationships with dermatoses

Authors
Redoules, D Tarroux, R Perie, J
Citation
D. Redoules et al., Epidermal enzymes: Their role in homeostasis and their relationships with dermatoses, SKIN PH APP, 11(4-5), 1998, pp. 183-192
Citations number
69
Categorie Soggetti
da verificare
Journal title
SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY
ISSN journal
14222868 → ACNP
Volume
11
Issue
4-5
Year of publication
1998
Pages
183 - 192
Database
ISI
SICI code
1422-2868(199807/10)11:4-5<183:EETRIH>2.0.ZU;2-2
Abstract
This review underlines the importance of different enzymes (beta-glucocereb rosidase, phospholipase A(2), proteases and cholesterol sulfatase) in the f ormation and maintenance of the epidermal barrier function. Certain disease s may be characterized by the lack or excess of one or more of these differ ent enzyme activities, altering the homeostatic equilibrium of the epidermi s. In addition to this, particular enzymes may show potential in the develo pment of novel dermocosmetic strategies.