An improved synthesis of the (E,Z)-Dienoate precursor of (+)-damavaricin Dvia a vinylogous Horner-Eadsworth-Emmons reaction

Authors
Chemler, SR Coffey, DS Roush, WR
Citation
Sr. Chemler et al., An improved synthesis of the (E,Z)-Dienoate precursor of (+)-damavaricin Dvia a vinylogous Horner-Eadsworth-Emmons reaction, TETRAHEDR L, 40(7), 1999, pp. 1269-1272
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
7
Year of publication
1999
Pages
1269 - 1272
Database
ISI
SICI code
0040-4039(19990212)40:7<1269:AISOT(>2.0.ZU;2-B
Abstract
An improved synthesis of the C(1)-C(5) (E,Z)-dienoate segment of (+)-damava ricin D precursor 3 was accomplished using the unsaturated phosphonate reag ent 9 in a (Z)-selective vinylogous Horner-Wadsworth-Emmons reaction. (C) 1 999 Elsevier Science Ltd. All rights reserved.