New nucleoside heteroanalogues: Desoxynucleoside selenocyanates

Authors
Belostotskii, AM Lexner, J Hassner, A
Citation
Am. Belostotskii et al., New nucleoside heteroanalogues: Desoxynucleoside selenocyanates, TETRAHEDR L, 40(6), 1999, pp. 1181-1184
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
6
Year of publication
1999
Pages
1181 - 1184
Database
ISI
SICI code
0040-4039(19990205)40:6<1181:NNHDS>2.0.ZU;2-4
Abstract
Naw nucleoside heteroanalogues, 5'- and 9'-desoxynucleoside selenocyanates and primary desoxysugar selenocyanates, were synthesized from activated nuc leoside and sugar derivatives and a new convenient seleno nucleophile, tetr abutylammonium selenocyanate. Tresylate-based activation of hydroxy functio ns turned out to be most successful for formation of these selenocyanates c ompared with mesylate- or triflate-based activation. (C) 1999 Elsevier Scie nce Ltd. All rights reserved.