A case of oropharyngitis caused by Malassezia pachydermatis in a 3-year-old
male Cocker Spaniel is reported. Recurrent episodes of pharyngitis were tr
eated with antibacterial antibiotics; when a final treatment after tooth ex
traction was unsuccessful, the dog was admitted to the clinic at the Depart
ment of Microbiology and Infectious Diseases at the Veterinary Faculty, Uni
versity of Zagreb. Bacteriological culture of enlarged tonsils revealed a m
ixed culture of Streptococcus sp., Staphylococcus sp. and Pasteurella sp. D
uring antibacterial treatment with amoxicillin plus clavulanic acid and met
ronidazole, lesions appeared in the oral cavity and mycological examination
of the lesions and enlarged tonsils revealed a pure culture of M. pachyder
matis. The patient was treated with ketoconazole, 10 mg kg(-1) twice daily
for 7 days when the lesions resolved. M. pachydermatis strains from the mou
th and from various sites on the dog's body had identical protein patterns
and DNA profiles which differed from strains from other animals.