Md. Garcia et al., Cytostatic activity of some phenolic acids of Scrophularia frutescens L. var frutescens, Z NATURFO C, 53(11-12), 1998, pp. 1093-1095
Citations number
10
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
The cytostatic activity of seven phenolic acids: coumaric, caffeic, ferulic
, gentisic, protocatechuic, syringic and isovanillic acid previously isolat
ed from Scrophularia frutescens has been evaluated against Hep-2 cells (der
ived from a human epidermoid carcinoma of the larynx) and McCoy cells (deri
ved from the synovial fluid in the knee joint of a patient suffering from d
egenerative arthritis). The compounds belonging to the cinnamic group prese
nt the highest activity.