9-(carboxymethyl)-6-chloropurine ethyl ester

Authors
Sood, G Schwalbe, CH Fraser, W
Citation
G. Sood et al., 9-(carboxymethyl)-6-chloropurine ethyl ester, ACT CRYST C, 54, 1998, pp. 1907-1909
Citations number
15
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
54
Year of publication
1998
Part
12
Pages
1907 - 1909
Database
ISI
SICI code
0108-2701(199812)54:<1907:9EE>2.0.ZU;2-C
Abstract
Alkylation of 6-chloropurine using ethyl bromoacetate gives a mixture of mo noalkyl regio-isomers from which the title compound, C9H9ClN4O2, was isolat ed in crystalline form. In both independent molecules, the side chain adopt s an extended conformation; its carboxymethyl-group plane intersects the pl anar heterocycle at angles of 60.1 (1) and 65.8 (1)degrees, respectively.