Coincidence of cytomegalovirus retinitis and central retinal vein occlusion in a patient with hemophilia B and AIDS

A 37-year-old man with hemophilia B, acquired immunodeficiency syndrome, an d a unilateral cytomegalovirus retinitis developed a central retinal vein o cclusion. This vascular complication occurred despite effective antiviral d rug treatment with improvement of the fundus and despite decreased blood co agulability due to hemophilia B. Additional analyses of thrombophilic param eters did not reveal hints of systemic thrombophilia, suggesting that toxic and inflammatory effects of cytomegalovirus itself were responsible for th e ophthalmologic aggravation.