Aspiration cytology of thyroid nodules is essentially designed to determine
the benign nature of the nodule in order to avoid purely diagnosis surgery
. It is reliable in the diagnosis of anaplastic papillary and medullary car
cinomas and most lymphomas, but is more problematical for the diagnosis of
the benign or malignant nature of Hurthle cell tumours and certain vesicula
r tumours, in which cytology reveals a suspicious, doubtful or undetermined
appearance. However, whether they are unambiguous or doubtful, fine needle
aspiration cytology results help the surgeon to define the therapeutic str
ategy under the best possible conditions. A therapeutic approach is propose
d, based on the formulation of aspiration cytology results into benign, mal
ignant, suspicious and inadequate.