Littoral cell angioma is a rare primitive vascular tumor of the the spleen
considered as benign. Its clinical presentation is non specific. The diagno
stic is based on histological and immunohistological analysis. The lesion i
s composed of anastomosing vascular channels often featuring papillary proj
ections. They are lined by tumoral cells which exhibit an immunoreactivity
for vascular and histiomonocytic markers. We report one case of littoral ce
ll angioma and we discuss the diagnosis and the histogenesis of this tumor.