Digital clubbing with or without hypertrophic osteoarthropathy may occur in
a variety of neoplastic diseases. We present the first description of digi
tal clubbing in a patient with progressive mantle cell lymphoma, in the abs
ence of any other apparent etiology. We suggest that clubbing might be a pa
raneoplastic manifestation in mantle cell lymphoma. The literature on digit
al clubbing in hematological neoplasms is reviewed.