In vitro activities of six new fluoroquinolones against Brucella melitensis

Authors
Trujillano-Martin, I Garcia-Sanchez, E Martinez, IM Fresnadillo, MJ Garcia-Sanchez, JE Garcia-Rodriguez, JA
Citation
I. Trujillano-martin et al., In vitro activities of six new fluoroquinolones against Brucella melitensis, ANTIM AG CH, 43(1), 1999, pp. 194-195
Citations number
19
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
1
Year of publication
1999
Pages
194 - 195
Database
ISI
SICI code
0066-4804(199901)43:1<194:IVAOSN>2.0.ZU;2-J
Abstract
We have tested the in vitro activities of eight fluoroquinolones against 16 0 Brucella melitensis strains. The most active was sitafloxacin (MIC at whi ch 90% of the isolates are inhibited [MIC90], 0.12 mu g/ml). In decreasing order, the activities (MIC(90)s) of the rest of the tested fluoroquinolones were as follows: levofloxacin, 0.5 mu g/ml; ciprofloxacin, trovafloxacin, and moxifloxacin, 1 mu g/ml; and ofloxacin, grepafloxacin. and gatifloxacin , 2 mu g/ml.