Glucose biosensors have proved an enormous success and are used by a g
rowing number of people with diabetes throughout the world. There are
several other notable biosensor developments that are already having a
n impact on analytical science, but the vast majority of possibilities
remain restricted to the realm of academic papers. Generic goals may
be identified which underpin more applied biosensor programmes and tac
kle some of the principal hurdles to the widespread adoption of biosen
sor technology for analysis. The design of integrated systems, approac
hes to patterning sensitive elements and methods to improve the sensit
ivity, stability and selectivity of biosensors are key areas which are
being tackled in our laboratories. This review considers some recent
progress under each of these headings and speculates on the socio-econ
omic impact of success.