Quality of survival after cardiopulmonary resuscitation

Background: Outcome of cardiopulmonary resuscitation (CPR) can be poor, in terms of life expectancy and quality of life. Objectives: To determine the impact of patient characteristics before, duri ng, and after CPR on these outcomes, and to compare results of the quality- of-life assessment with published studies. Methods: In a cohort study, we assessed by formal instruments the quality o f life, cognitive functioning, depression, and level of dependence of survi vors after in-hospital CPR. Follow-up was at least 3 months after discharge from the hospital (tertiary care center). Results: Of 827 resuscitated patients, 12% (n = 101) survived to follow-up. Of the survivors, 89% participated in the study. Most survivors were indep endent in daily life (75%), 17% were cognitively impaired, and 16% had depr essive symptoms. Multivariate regression analysis showed that quality of li fe and cognitive function were determined by 2 factors known before CPR-the reason for admission and age. Factors during and after resuscitation, such as prolonged cardiac arrest and coma, did not significantly determine the quality of life or cognitive functioning of survivors. The quality of life of our CPR survivors was worse compared with a reference group of elderly i ndividuals, but better than that of a reference group of patients with stro ke. The quality of life did not importantly differ between the compared stu dies of CPR survivors. Conclusions: Cardiopulmonary resuscitation is frequently unsuccessful, but if survival is achieved, a relatively good quality of life can be expected. Quality of life after CPR is mostly determined by factors known before CPR . These findings may be helpful in informing patients about the outcomes of CPR.