A high-Mr glycoprotein fraction from cow's milk potent in inhibiting replication of human rotavirus in vitro

Authors
Kanamaru, Y Etoh, M Song, XG Mikogami, T Hayasawa, H Ebina, T Minamoto, N
Citation
Y. Kanamaru et al., A high-Mr glycoprotein fraction from cow's milk potent in inhibiting replication of human rotavirus in vitro, BIOS BIOT B, 63(1), 1999, pp. 246-249
Citations number
26
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
63
Issue
1
Year of publication
1999
Pages
246 - 249
Database
ISI
SICI code
0916-8451(199901)63:1<246:AHGFFC>2.0.ZU;2-Q
Abstract
Rotavirus is the major cause of infectious diarrhea in infants and young ch ildren all over the world. We have found that a high-M-r glycoprotein fract ion from cow's milk is potent in inhibiting replication of human rotaviruse s in vitro. Since the activity seems to be unique and specific, this fracti on may be useful as a novel agent for treatment or prevention of rotavirus diarrhea.